Transfusion-associated microchimerism
نویسندگان
چکیده
منابع مشابه
Transfusion-associated microchimerism in combat casualties.
BACKGROUND Fresh whole blood (FrWB) is routinely used in the resuscitation of combat casualties in Operation Iraqi Freedom and Operation Enduring Freedom. However, studies have shown high rates (20%-40%) of transfusion-associated microchimerism (TA-MC) in civilian trauma patients receiving allogenic red blood cell (RBC) transfusions. We explored the incidence of TA-MC in combat casualties recei...
متن کاملTRANSFUSION MEDICINE Brief report The TNF ( 308A) polymorphism is associated with microchimerism in transfused trauma patients
Microchimerism (MC), defined as the persistence of allogeneic cells at low concentrations, is well documented in transfused trauma patients. We hypothesized that genetic polymorphisms linked to cytokine production could contribute to trauma-induced immune modulation and development of microchimerism after transfusion of trauma patients. We used high-throughput SYBR-green-based genotyping of sin...
متن کاملTRANSFUSION MEDICINE Survival of Donor Leukocyte Subpopulations in Immunocompetent Transfusion Recipients: Frequent Long-Term Microchimerism in Severe Trauma Patients
We recently reported detection of a transient increase in circulating donor leukocytes (WBCs) in immunocompetent recipients 3 to 5 days posttransfusion (tx) (Blood 85:1207, 1995). We have now characterized survival kinetics of specific donor WBC subsets in additional tx populations. Eight female elective surgery patients (pts) were sampled pre-tx and on days 1, 3, 5, 7, and 14 post-tx. Ten fema...
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Transfusion-associated bacterial sepsis (TABS) is caused by bacteria present in blood components. It is one of the earliest recognized adverse transfusion-associated reactions. Blood components most often become contaminated while blood is being collected from a donor; more seldom in the case of asymptomatic bacteremia or erroneous blood processing procedures (1). Although the risk for transfus...
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From October 2010 to December 2015, we screened a total of 1716 babies. 809 babies were from well-baby nurseries and 907 babies were from neonatal intensive care unit. 299 babies failed the first screen, but only 66 out of 299 appeared for rescreen. Eighteen babies failed the rescreen and were recommended BERA testing. However, none of the babies turned up for BERA testing or could not be track...
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ژورنال
عنوان ژورنال: Vox Sanguinis
سال: 2007
ISSN: 0042-9007
DOI: 10.1111/j.1423-0410.2007.00954.x